For a long time did not update the blog, now is the medical industry are looking for the golden season of products, participated in several meetings to see, the domestic production of VSD dressing manufacturers and several, most of the same, not really master the core technology. Here is a reminder to business friends to evaluate comprehensively when choosing products.
Today to talk to you about the mechanism of negative pressure closure drainage, before more or less mentioned a point, mainly divided into the following points hope to help you.
1. The closure is maintained by the indirect low negative pressure as the drainage power, and at the same time, the drainage area is isolated from the outside world, effectively preventing pollution and cross-infection;
2. Indirect low negative pressure can drain the exudate, necrotic tissue and bacteria of the wound, so that the drainage area can achieve "zero accumulation", and the wound can quickly obtain a clean environment;
3. Increase wound blood supply, improve wound microcirculation, and promote granulation tissue growth. VSD can significantly enhance the proliferation of superficial dermal vascular endothelial cells and fibroblasts in the wound margin tissues and the density of microvascular vessels. In recent years, some experimental studies have found that the blood flow to the wound after negative pressure is applied is significantly increased compared with before negative pressure.
4. Regulate the activity of gelatin enzymes in chronic wounds, improve microcirculation within the foundation, inhibit the degradation of collagen and gelatin, and promote the healing of chronic wounds
5. Reduce pertussis and reduce vascular permeability.
6. Increase the neuropeptide sP and P substances secreted by peripheral nerve ends in the wound. VSD affects the expression of endogenous epidermal cell growth factor by enhancing the expression of P substance secreted by peripheral nerve endings and calcitonin-related gene peptides, and has a significant effect on promoting wound healing.
7. In recent years, studies believe that proto-oncogenes play an important role in early embryonic development, cell growth control, cell differentiation and tissue repair. In the process of VSD promoting the healing of chronic wounds, it can quickly start the healing process of skin wounds, reduce the apoptosis of repair cells, and accelerate wound healing.
8. Enhance the inflammatory response of infected wounds. It can cause the infiltration of wound lymphocytes to subside quickly, the collagen synthesis during the hyperplasia period appears earlier, and the contractile fiber synthesis can be increased during the repair period.
9. Promote wound healing and inhibit secondary necrosis of infected wounds.